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Digital Silicon Photomultiplier Principles Technology and Applications to Positron Emission Tomography

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The Silicon Photomultiplier for application to high ~ Positron Emission Tomography (PET) for small animal studies requires high-resolution gamma cameras with high sensitivity. Traditionally, inorganic scintillators are used and, in recent times, coupled to position sensitive PMTs to achieve a higher resolution. Such PSPMTs are costly, operated at high voltage and have a relatively low packing .

(PDF) Plug Silicon Photomultiplier for the & Imaging PET ~ Schematics of a digital silicon photomultiplier with a dedicated read-out digital electronics for each microcell. . based on the technique of positron emission tomography. We used the Plug and .

The Digital Silicon Photomultiplier / IntechOpen ~ The Silicon Photomultipliers (SiPMs) are the new step in the development of the modern detection structures in the area of low photon flux detection with a unique capability of detection up to the single photons. The Silicon Photomultiplier intrinsically represents a digital signal source on the elementary cell level. The materials and technology of SiPMs are consistent with the modern .

Digital Silicon Photomultiplier – Volume 1: Physics and ~ <p>The book is intended as a detailed guide to use and evaluate the modern digital technology to build modern PET systems. Digital Positron Emission Tomography represents the most modern trend among non-invasive functional nuclear imaging techniques. The term digital is interpreted both in terms of hardware configuration and in terms of data stream analysis. Modern miniaturized sensors .

Sensors for Positron Emission Tomography Applications ~ Positron emission tomography (PET) imaging is an essential tool in clinical applications for the diagnosis of diseases due to its ability to acquire functional images to help differentiate between metabolic and biological activities at the molecular level. One key limiting factor in the development of efficient and accurate PET systems is the sensor technology in the PET detector.

Application of Silicon Photomultipliers to Positron ~ The silicon-photomultiplier (SiPM) is becoming the device of choice for different applications, for example in fast timing like in time of flight positron emission tomography (TOF-PET) and in high .

The Silicon Photomultiplier for application to high ~ The Silicon Photomultiplier (SiPM) is a silicon diode detector that shows great promise as a photodetector for scintillators and hence application in nuclear medicine imaging applications.

Instrumentation for Time-of-Flight Positron Emission ~ Positron emission tomography (PET) is a molecular imaging modality that provides information at the molecular level. This system is composed of radiation detectors to detect incoming coincident annihilation gamma photons emitted from the radiopharmaceutical injected into a patient’s body and uses these data to reconstruct images. A major trend in PET instrumentation is the development of .

Digital silicon photomultiplier readout of a new fast and ~ A variety of scintillators are used to detect radiation in fields such as gamma spectroscopy and nuclear medicine including positron emission tomography (PET) and single photon emission computed tomography (SPECT) , , .Desirable scintillator properties for PET include high luminosity, high density, high stopping power and fast rise and decay time constants.

Application of Silicon Photomultipliers to Positron ~ Historically, positron emission tomography (PET) systems have been based on scintillation crystals coupled to photomultipliers tubes (PMTs). However, the limited quantum efficiency, bulkiness, and relatively high cost per unit surface area of PMTs, along with the growth of new applications for PET, offers opportunities for other photodetectors.

(PDF) Time-Based Readout of a Silicon Photomultiplier ~ Time-Based Readout of a Silicon Photomultiplier (SiPM) for Time of Flight Positron Emission Tomography (TOF-PET) Article (PDF Available) in IEEE Transactions on Nuclear Science 58(3):597 - 604 .

Volume 4 Issue 1 / Journal of Medical Imaging ~ The Journal of Medical Imaging allows for the peer-reviewed communication and archiving of fundamental and translational research, as well as applications, focused on medical imaging, a field that continues to benefit from technological improvements and yield biomedical advancements in the early detection, diagnostics, and therapy of disease as well as in the understanding of normal conditions.

Silicon Photomultiplier for the Plug & Imaging PET system ~ We propose the design of a Silicon Photomultiplier at the 180 nm GLOBALFOUNDRIES BCDLITE CMOS technology node. We perform a characterization of the device, in comparison with other results obtained a CMOS technology node and we investigate the limits and strengths of this approach. Finally we show possible future applications of the SiPM in Nuclear Medicine, in particular to digital positron .

Sensors / Free Full-Text / Design and Evaluation of LYSO ~ Positron emission tomography (PET) has a wide range of applications in the treatment and prevention of major diseases owing to its high sensitivity and excellent resolution. However, there is still much room for optimization in the readout circuit and fast pulse sampling to further improve the performance of the PET scanner. In this work, a LIGHTENING&reg; PET detector using a 13 &times; 13 .

(PDF) Development of a back-contact, scalable silicon ~ The long term goal of the work described in this paper is to develop a scalable silicon photomultiplier (SiPM) array technology with back-side contacts to facilitate integration with scintillating .

Solid-State Digital Photon Counting PET/CT / SpringerLink ~ Abstract. In this chapter, we describe the solid-state digital photon counting (DPC) clinical PET/CT, Vereos TF 64, a system differing from other SiPM-based PET/CT systems by directly coupling every lutetium-yttrium oxyorthosilicate (LYSO) scintillator with its own DPC detector sensor.

US8923588B2 - Method and system for improved TOF PET ~ A time of flight positron emission tomography apparatus ( 100 ) includes a detector ( 106 ), a data acquisition system ( 120 ), a coincidence system ( 122 ) and a reconstructor ( 129 ). Various elements of an imaging chain influence the temporal resolution of the system ( 100 ) so that positron data collected along different lines of response is characterized by different temporal resolutions.

Silicon Photomultiplier Technology at STMicroelectronics ~ Silicon Photomultiplier Technology at STMicroelectronics Abstract: In this paper we present the results of the first electrical and optical characterization performed on 1 mm 2 total area Silicon Photomultipliers (SiPM) fabricated in standard silicon planar technology at the STMicroelectronics Catania R&D clean room facility.

Positron emission tomography - Wikipedia ~ Positron emission tomography (PET) is a functional imaging technique that uses radioactive substances known as radiotracers to visualize and measure changes in metabolic processes, and in other physiological activities including blood flow, regional chemical composition, and absorption.Different tracers are used for various imaging purposes, depending on the target process within the body.

Advanced Functional Tumor Imaging and Precision Nuclear ~ The purpose of this article is to provide a brief overview of the background, basic principles, technological evolution, clinical capabilities, and future directions for functional tumor imaging as PET evolves from the conventional photomultiplier tube-based platform into a fully digital detector acquisition platform. The recent introduction of solid-state digital photon counting PET detector .

Crystals / Free Full-Text / Evaluation of Various ~ The performance of radiation detectors used in positron-emission tomography (PET) is determined by the intrinsic properties of the scintillators, the geometry and surface treatment of the scintillator crystals and the electrical and optical characteristics of the photosensors. Experimental studies were performed to assess the timing resolution and energy resolution of detectors constructed .

Recent developments in PET detector technology - IOPscience ~ Herbert D J, Moehrs S, D'Ascenzo N, Belcari N, Del Guerra A, Morsani F and Saveliev V 2007 The silicon photomultiplier for application to high-resolution positron emission tomography Nucl. Instrum. Methods Phys. Res. A 573 84-7. Crossref

PET System Technology Designs for Achieving Simultaneous ~ Abstract. The combination of positron emission tomography (PET) and magnetic resonance imaging (MRI) shows promise to be a powerful tool for disease characterization as it enables the simultaneous measurement of molecular, physiological, and anatomical information of the patient.

Update on novel trends in PET/CT technology and its ~ Although single-photon emission CT (SPECT) has not changed much since its beginning [most SPECT are still made of sodium iodide (NaI) photomultiplier tube (PMT) detectors as invented by Anger 1 in 1958 and equipped with a parallel hole collimator], positron emission tomography (PET) has seen several major improvements since the proof of concept made by Burnham and Brownell 2 in 1972.

Integrated Front-end Electronics for Silicon ~ The 4D-MPET project aims to design a positron emission tomography detection module capable of working inside a magnetic resonant imaging system. The proposed detector will feature a three-dimensional architecture based on two tiles of silicon photomultipliers coupled to a single LYSO scintillator on both its faces.